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Lifecycle Modeling and Simulation: Part II. Applications in Clinical Development
Quintiles Vision Series
This three-part series explores the potential of modeling and simulation practice throughout the drug development process.
Part 1 discussed the concept of lifecycle modeling and simulation and its current applications in early drug development.
Part 2 considers expanding applications in Phases I-III, including portfolio management.
Part 3 will examine modeling and simulation practice and potential in the post-approval arena, including applications aimed at improving healthcare…This three-part series explores the potential of modeling and simulation practice throughout the drug development process.
Part 1 discussed the concept of lifecycle modeling and simulation and its current applications in early drug development.
Part 2 considers expanding applications in Phases I-III, including portfolio management.
Part 3 will examine modeling and simulation practice and potential in the post-approval arena, including applications aimed at improving healthcare planning and delivery.Other authorsSee publication -
Lifecycle Modeling and Simulation: Current Practice and Future Impact on Healthcare Innovation and Delivery
Quintiles
The paper addresses how new modeling and simulation applications range from genetic studies and identifying drug targets to simulated clinical trials. It covers how modeling and simulation can test assumptions and make predictions that improve planning and decision making across the full spectrum of therapeutic innovation, and how it enriches and quantifies scientific thinking by bringing experts together to consider optimal approaches
Other authorsSee publication -
Optimising Patient-Centric Services: a Tailored Solution
Journal for Patient Compliance, 1:3 36-40
Patient behaviour – the largest single factor in compliance and wellness – can be influenced through a suite of patientcentric services (PCS) allowing the design and implementation of programmes that support better patient outcomes while reducing healthcare costs. This approach is based on a solid understanding of factors that influence patient behavior, and then employing technology and predictive analytics to change that behaviour. This paper discusses the need for a more sophisticated…
Patient behaviour – the largest single factor in compliance and wellness – can be influenced through a suite of patientcentric services (PCS) allowing the design and implementation of programmes that support better patient outcomes while reducing healthcare costs. This approach is based on a solid understanding of factors that influence patient behavior, and then employing technology and predictive analytics to change that behaviour. This paper discusses the need for a more sophisticated approach to PCS that includes the use of predictive analytics for risk modelling, and defines medication adherence, health and wellness programmes, and remote patient monitoring.
Other authorsSee publication -
Regulatory Implications of Technology Platforms for Patient-Centric Service
Regulatory Affairs Professionals Society, Regulatory Focus 16:11 24-34
Patient behavior is the largest single factor in health status and outcomes, but influencing it has proven challenging, with few patient-focused behavioral interventions demonstrated to be effective. Recent evidence suggests that patient behavior can only be influenced by targeted and personalized multi-channel interventions that take each patient’s unique characteristics and motivators into account.4,5 These targeted and personalized interventions, such as remote alerts and real-time vital…
Patient behavior is the largest single factor in health status and outcomes, but influencing it has proven challenging, with few patient-focused behavioral interventions demonstrated to be effective. Recent evidence suggests that patient behavior can only be influenced by targeted and personalized multi-channel interventions that take each patient’s unique characteristics and motivators into account.4,5 These targeted and personalized interventions, such as remote alerts and real-time vital signs and medication monitoring, are rooted in a deep understanding of psychological, clinical and environmental factors that influence patient behavior. Targeted interventions based on such insights also have the potential to greatly increase patient and physician engagement by providing real-time feedback during the course of treatment. This offers potential for changes in therapy, helping to avoid hospitalizations.
Other authorsSee publication -
Biosensors as a source of patient insights
Patients Week 2011
See publicationA question and answer session where I address the emerging space of wearable biosensors which are promising tools to improve outcomes and cut costs
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Patients’ Week 2011: Enhancing Patient Value
Patient's Week 2011
See publicationIn this article I explain the importance of tailoring programs to patients based on cultural and psychographic factors
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